24 papers
This study of British Columbia's GetCheckedOnline service reveals that while a small subset of high-risk users accounts for the majority of tests, overall utilization aligns with prevention needs rather than indiscriminate overuse, supporting a stewardship approach focused on risk-based education rather than universal restrictions.
This qualitative study in Uganda finds that while clients, providers, and policymakers view integrating point-of-care STI testing into community pharmacies as a highly acceptable strategy to improve accessibility, speed, and antimicrobial resistance control, its successful implementation requires addressing barriers such as stigma, privacy concerns, and supply chain sustainability.
This study in Kilifi County, Kenya, reveals that female genital schistosomiasis affects 36% of women of reproductive age but is largely missed by routine urine microscopy, as 72% of infected women showed no detectable urinary eggs, highlighting the critical need for genital sampling and molecular diagnostics in control strategies.
This qualitative study of 22 Dutch individuals experiencing unexpected pregnancy utilizes a life course perspective and Schlossberg's transition theory to reveal that adjustment patterns vary from instant to triggered to ambiguous "unfolding," with the latter highlighting that adaptation often remains an ongoing process for those with stable life trajectories and strong aspirations.
This cross-sectional baseline study of sexually active HIV-negative adolescent girls and young women in rural South Africa reveals that while vaginal-stimulating product use is highly prevalent, it is significantly associated with cervical ectopy in adults and shows exploratory links to specific STIs and HPV-16 in adolescents, underscoring the need for further longitudinal research to clarify biological risks and inform culturally responsive health interventions.
A cross-sectional study conducted in Kinshasa between June and December 2023 revealed an 18% prevalence of *Chlamydia trachomatis* infection among low-income pregnant women, with the highest rates observed in married women aged 25–35 and significant associations with vaginal symptoms and adverse pregnancy outcomes such as prematurity and spontaneous abortion.
This qualitative study reveals that STI service delivery for internally displaced persons in Nigeria is critically undermined by HIV-centric vertical financing, weak implementation of policies, and sociocultural barriers, necessitating a strategic rebalancing of funding and strengthened health systems to ensure equitable access.
This meta-analysis of 20 studies reveals that homeless women face disproportionately high rates of sexual assault, with a pooled lifetime prevalence of 39.2% and a 12-month prevalence of 22%, highlighting particularly elevated risks for those with disabilities, mental illness, or LGBTQ+ identities and underscoring the urgent need for tailored public health interventions.
This study successfully culturally adapted and psychometrically validated the Acceptability, Appropriateness, and Feasibility measures for evaluating postpartum family planning interventions among Ghanaian midwives and nurses, finding that while the adapted tools are reliable, their abridged versions demonstrate superior construct validity compared to expanded versions.
This study reports the first successful human case of autologous transplantation of cryopreserved immature testicular tissue, demonstrating that such grafts can survive long-term storage, revascularize, and restore complete spermatogenesis in a patient who underwent gonadotoxic therapy during childhood.
A quasi-experimental pre-post study in rural northeastern Uganda demonstrates that a community-based, peer-led sexual and reproductive health education intervention significantly reduced risky sexual behaviors and improved comprehensive knowledge among adolescent girls and young women, though further robust research is needed to address persistent contextual risk factors.
This study utilizes natural language processing to analyze over 90,000 Reddit posts and comments, revealing that anonymous online communities serve as vital support infrastructures for men with infertility by facilitating clinical sense-making, emotional validation, and collective coping while mitigating the stigma often associated with male infertility in offline settings.
This community-based cross-sectional study conducted in October 2023 across five districts in Ethiopia's Oromia and Gambella regions reveals a 60.9% family planning utilization rate, identifying limited transport access, low household wealth, low partner education, and unintended pregnancy as significant barriers while noting that farming women are more likely to utilize these services.
This large-scale genome-wide study utilizing UK Biobank data reveals that sex hormones causally influence plasma glycodelin levels, suggesting that previously observed associations between glycodelin and reproductive diseases are likely driven by hormonal effects rather than a direct causal role of glycodelin itself.
This study demonstrates that Performance-Based Financing significantly improved the utilization and quality of obstetric care in Nkambe Health District, Cameroon, by increasing service attendance, provider knowledge, and patient satisfaction, leading to a recommendation for its scale-up with attention to cost and staffing.
This study identifies biallelic loss-of-function variants in the HIPK4 gene as a novel autosomal-recessive cause of teratozoospermia and male infertility, characterized by 100% abnormal sperm head morphology, while also highlighting the genetic heterogeneity within a single family where distinct mutations in HIPK4 and DNAH17 underlie different sperm defects.
A 2024 UK online survey of 2,758 men and gender-diverse people who have sex with men found that the 8% who reported chemsex-associated drug use exhibited significantly higher sexual risk behaviors, poorer mental wellbeing, and greater engagement with sexual health services compared to non-users, highlighting the critical role of these services in providing harm reduction support.
The EARLY-PREG study is a preconception longitudinal cohort in Chile that systematically collects maternal biological samples across menstrual cycles to characterize time-dependent molecular signatures of maternal-embryonic signaling during the peri-implantation window by comparing conception and non-conception cycles.
This study demonstrates that a high-throughput dia-PASEF proteomics workflow significantly outperforms conventional DDA-FracOffline methods by increasing protein coverage by approximately 50% and enhancing quantitative reproducibility, thereby enabling more robust longitudinal analysis of cervicovaginal fluid dynamics across the menstrual cycle.
A London-wide survey of 97 women with limited English proficiency reveals a strong willingness to travel across maternity networks for classes delivered in their native language, supporting the development of collaborative, cross-trust models to standardize and centralize multilingual antenatal education to improve equity and reduce service duplication.